Hearing, Vision Loss Combo a Colossal Risk for Cognitive Declin

The combination of hearing loss and vision loss is linked to an eightfold increased risk of cognitive impairment, new research shows. Investigators analyzed data on more than 5 million US seniors. Adjusted results show that participants with hearing impairment alone had more than twice the odds of also having cognitive impairment, while those with vision … Read more

A Cup of Cranberries a Day Tied to Better Memory

For healthy middle-aged and older adults, adding cranberries to the diet may help improve memory and brain function, in addition to lowering LDL cholesterol, new research suggests. Results from a randomized, placebo-controlled trial of adults aged 50-80 years showed that consuming freeze-dried cranberry extract, which is equal to one cup of fresh cranberries, for 12 … Read more

A Computerized Test May Help Detect Cognitive Impairment

The study covered in this summary was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaways The Loewenstein-Acevedo Scales for Semantic Interference and Learning, Brief Computerized Version (LASSI-BC) measured early cognitive change in patients with Alzheimer’s disease (AD) and was able to differentiate between cognitively unimpaired (CU) and amnestic … Read more

High MVA Injury Rate in Early-Onset Dementia a Cause for Concern

Individuals diagnosed with young-onset dementia (YOD) have an alarmingly high risk of serious injury because of motor vehicle accidents — both as pedestrians and drivers. Results from a longitudinal, registry-based cohort study showed that compared with the general population, YOD patients had an almost twofold increased risk of MVA-related injury. Dr Jiun-Yi Wang “These findings … Read more

Best Antioxidants to Prevent Age-Related Dementia Identified?

Higher levels of specific carotenoid antioxidants in blood may help guard against age-related dementia, new research suggests. Investigators found that individuals with the highest serum levels of lutein+zeaxanthin and beta-cryptoxanthin at baseline were less likely to have dementia decades later than their peers with lower levels of these antioxidants. Lutein and zeaxanthin are found in … Read more

Residential Green Space Linked to Better Cognitive Function

Dr Marcia Pescador Jimenez Exposure to green space may boost cognitive function, new research suggests. Results of a large prospective study showing increasing exposure to residential green space was associated with significantly higher scores on cognitive function measures in middle-aged women compared with women who had less exposure. This association may be explained by a … Read more

Noninvasive Biomarkers for Alzheimer Disease?

The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Higher expression and upregulation of fatty acid pathways and the phospholipids associated phosphatidylethanolamine (PE) and diacylglycerol (DAG) were with smaller whole-brain volumes and may be linked with neurodegeneration and Alzheimer’s disease (AD). Overall, … Read more

Depression Biomarkers: Which Ones Matter Most?

Multiple biomarkers of depression involved in several brain circuits are altered in patients with unipolar depression. The first comprehensive meta-analysis of all biomarkers quantified to date in cerebrospinal fluid (CSF) of individuals with unipolar depression showed that several could be “clinically meaningful” because they suggest neuroimmunological alterations, disturbances in the blood–brain-barrier, hyperactivity in the hypothalamic-pituitary-adrenal … Read more