Lithium May Lower Osteoporosis Risk in Bipolar Disorder

NEW ORLEANS — People with bipolar disorder – particularly men – show a significantly increased risk of osteoporosis, compared with the general population, but treatment with lithium appears to offer a significant protective effect against the bone disease, according to results from the largest study of its kind. Dr Soren Ostergaard “Our findings emphasize that … Read more

Missed Appointments: Treating Executive Dysfunction

Maybe you know some of these patients: they may come late or not show up at all. They may have little to say and minimize their difficulties, often because they are ashamed of how much effort it takes to meet ordinary obligations. They may struggle to complete assignments, fail classes, or lose jobs. And being … Read more

Does Noninvasive Brain Stimulation Augment CBT for Depression?

Noninvasive brain stimulation does not appear to augment cognitive behavioral therapy (CBT) in patients with major depressive disorder (MDD), new research shows. Results of a multicenter, placebo-controlled randomized clinical trials showed adjunctive transcranial direct current stimulation (tDCS) was not superior to sham-tDCS plus CBT or CBT alone. “Combining these interventions do not lead to added … Read more

Adherence to ADHD Meds May Lower Unemployment Risk

Adherence to medication for attention-deficit/hyperactivity disorder (ADHD) is linked to a significantly lower risk for illness, particularly among women, new research suggests. Investigators analyzed data for almost 13,000 working-age adults with ADHD and found ADHD medication use during the previous 2 years was associated with a 10% lower risk for long-term unemployment in the following … Read more

Maternal Autoimmune Diseases Up Risk of Mental Illness in Children

Mental disorders were significantly more likely in children whose mothers had one of five common autoimmune diseases, a new study found. Previous research has linked both maternal and paternal autoimmune diseases and specific mental disorders, such as attention-deficit/hyperactivity disorder (ADHD), but most of these studies focused on specific conditions in relatively small populations. The new … Read more

Psychiatric Illness Associated With Eosinophilic Esophagitis

People with eosinophilic esophagitis (EoE) may run an increased risk of mood disorders, anxiety, and attention-deficit/hyperactivity disorder (ADHD) and should be screened for those conditions, researchers say. “It’s important to know that there is an elevated risk of those diagnoses, so you have that in mind when you treat your patients. You can assess their … Read more

Brief Intervention Effective, Durable for Schizophrenia

Metacognitive training (MCT) is effective in reducing positive and negative symptoms of schizophrenia, new research suggests. MCT for psychosis is a brief intervention that “combines psychoeducation, cognitive bias modification, and strategy teaching but does not directly target psychosis symptoms.” Results from a meta-analysis of 40 studies with more than 1,800 total participants with schizophrenia showed … Read more

Microdosing Psychedelics: Untapped Potential in Psychiatry?

In her month-long memoir, A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life (Knopf, 2017), author Ayelet Waldman turns herself into a one-woman experiment. Over a single month she takes one tenth of a recreational dose of LSD every third day. She plots her emotions, her … Read more

NP-led Care Improves Quality of Life for Multiple Sclerosis Patients

The study covered in this summary was published in medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Depression improved with add-on nurse practitioner (NP)–led care in comparison with usual neurologist care at 3 and 6 months for patients with multiple sclerosis (MS): satisfaction with care was the same in both … Read more

Major Mental Illness Linked to Higher CVD Risk, Even in Young

Serious mental illnesses such as bipolar disorder and schizophrenia are associated with a significant increase in cardiovascular risk, particularly among younger age groups, a new observational study suggests. Prior research has shown that people with schizophrenia and bipolar disorder die 10 to 20 years earlier than those without serious mental illness and that the leading … Read more