More Evidence Insomnia Contributes to Cognitive Decline

A new study provides more evidence that insomnia may contribute to cognitive decline in older adults and shows that difficulty falling asleep in midlife may be most indicative of future cognitive impairment. Investigators found that having trouble falling asleep most nights (vs rarely/never) was equivalent to the effect of 2 to 3 years of aging … Read more

Patients With Schizophrenia Twice as Likely to Develop Dementia?

Patients with psychotic disorders such as schizophrenia are more than twice as likely as those without a psychotic disorder to eventually develop dementia, new research suggests. Results from a review and meta-analysis of almost 13 million total participants from nine countries showed that, across multiple different psychotic disorders, there was a 2.5-fold higher risk of … Read more

1 in 7 Mortality Postsurgery; ECT and MDE; and Monkeypox News

One in Seven Older Adults Die Within 1 Year After Surgery One in seven older adults die within 1 year of major surgery. The risk for mortality is higher among people older than 80 years or who are frail or may have dementia, according to a new study of community-living individuals. The study did not … Read more

One Type of Older Diabetes Drug Cuts Dementia Risk, Another Ups It

Thiazolidinediones (TZDs), such as pioglitazone, appear to be protective against dementia whereas sulfonylureas appear to increase the risk, a new observational study in patients with type 2 diabetes suggests. The data, obtained from nationwide electronic medical from the US Veterans Affairs Administration, yielded a 22% lower risk of dementia with TZD monotherapy and a 12% … Read more

Not Just a Bad Dream: Nightmares May Predict Dementia

Nightmares in healthy middle-aged and older adults may be an independent risk factor for cognitive decline and dementia, particularly in men, new research suggests. Results from a large cohort study showed that healthy middle-aged adults who had bad dreams at least once a week were four times more likely to experience cognitive decline over the … Read more

Urgent Need for Research Into Psychedelic Tx for Older Adults

Older age is associated with many health conditions that could potentially benefit from psychedelic-assisted therapy, yet very few older adults have been included in clinical trials of psychedelics, new research shows. “Geriatric psychiatrists and others caring for older adults are interested in how much is known about psychedelic use in older adults,” study investigator C. … Read more

Watching TV, Using Computer Have Opposite Ties to Dementia Risk

Watching TV may increase your risk of dementia, while using a computer may lower it, new research suggests. The relationship to dementia with these activities remained strong no matter how much physical activity a person did, the authors wrote in Proceedings of the National Academy of Sciences. Both watching TV and using a computer have … Read more

Treating the Growing Population of Centenarians

For about the past year, Priya Goel, MD, can be seen cruising around the island of Manhattan as she makes her way between visits to some of New York City’s most treasured residents: a small but essential group of patients born before the Empire State Building scraped the sky and the old Yankee Stadium had … Read more

Metformin Linked With Less Dementia in People With Diabetes

The study covered in this summary was published on medRxiv as a preprint and has not yet been peer reviewed. Key Takeaways Why This Matters Type 2 diabetes is a well-established risk factor for dementia and PD, suggesting that metformin might reduce the risk of these neurodegenerative diseases, but findings from prior studies have been … Read more

Clean House, Healthy Mind? Chores May Lower Dementia Risk

Participating in certain physical and mentally stimulating activities may be protective against dementia, new research suggests. In a large prospective cohort study, individuals who regularly engaged in stenuous exercise had a 35% less risk of dementia, those who consistently did household chores had a 21% lower risk, and those who reported seeing friends and family … Read more