MRI Plus Deep Learning Models Estimate Brain-Aging

The covered study in this summary was published in bioRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Using the Layer-wise Relevance Propagation algorithm and various structural MRI modalities (T1-weighted, fluid-attenuated inversion recovery [FLAIR]and susceptibility-weighted magnitude images [SWI]), brain age can be estimated. The structural abnormalities found were changes in the … Read more

Hormonal Contraceptives Protective Against Suicide?

Contrary to previous analyses, women without a history of psychiatric illness who take combined hormonal contraceptives do not have an increased risk for attempted suicide but may have a reduced risk with extended use, new research suggests. In a study of more than 800 women younger than age 50 who attempted suicide and more than … Read more

Genetic Testing for Best Antidepressant Accurate, Cost-Effective

Genetic testing to determine the best antidepressant for patients with major depressive disorder (MDD) has the potential to lead to an optimal drug choice on the first try and reduce healthcare costs, new research suggests. CYP2D6 and CYP2C19, from the cytochrome P450 family, are involved in the metabolism and elimination of various molecules, including medications. … Read more

In Utero COVID Exposure Tied to Developmental Differences

COVID-19 in during pregnancy has been linked to a small but significant effect on infant neurodevelopment, suggests a small-scale analysis that points to the need for further study and monitoring during pregnancy. The study included 24 pregnant women, half of whom had COVID-19 during pregnancy, and their offspring. It showed impairments at 6 weeks of … Read more

Disasters Abroad a Major Trigger for Mental Illness in Expats

The 2020 explosion that rocked Beirut, killing more than 200, injuring more than 7000 and causing millions of dollars in damage had a significant impact on the mental health of Lebanese expatriates, leaving many grappling with anxiety, depression, and posttraumatic stress disorder (PTSD) , results of a new survey show. The findings highlight the importance … Read more

Burnout ‘Highly Prevalent’ in Psychiatrists Across the Globe

Burnout in psychiatrists is “highly prevalent” across the globe, new research shows. In a review and meta-analysis of 36 studies and more than 5000 psychiatrists in European countries, as well as the United States, Australia, New Zealand, India, Turkey, and Thailand, results showed that 25% of respondents met criteria for burnout, as measured by the … Read more

Ukraine and PTSD: How Psychiatry Can Help

The war in Ukraine is resulting in a devastating loss of life, catastrophic injuries, and physical destruction. But the war also will take an enormous mental health toll on millions of people, resulting in what I think will lead to an epidemic of posttraumatic stress disorder. Think about the horrors that Ukrainians are experiencing. Millions … Read more

Psychiatrist Steps Up to Deliver Precious Cargo to Ukraine

Just days after Russia invaded Ukraine, child and adolescent psychiatrist Dennis Ougrin, MBBS, PhD, and his wife Roxanne Litynska, who are both originally from Lviv, drove their car full of critical cargo from London to Przemyśl — a Polish border town that was experiencing a huge influx of refugees fleeing the war. The vehicle was … Read more

Methylphenidate Is Overprescribed to Children in France

The prevalence of attention-deficit/hyperactivity disorder (ADHD) is difficult to evaluate, and the diagnosis is based primarily on clinical criteria. In 2008, a French study estimated the prevalence to be between 3.5% and 5.6%, but the study’s design was questionable. Treatment of this disorder consists first and foremost in educational, social, and psychotherapeutic management. Only if … Read more

Calls for Caution on Gender Reassignment in Adolescents

France — Demand for gender reassignment surgery in children and adolescents has increased in the United States and Europe over the past few years. For its part, the French National Academy of Medicine has urged that caution be exercised when it comes to the therapies involved and advised that the psychological support phase be extended. … Read more