Plasma Biomarkers Predict COVID Neurologic Complications

SAN DIEGO – Even after recovery of an acute COVID-19 infection, some patients experience extended or even long-term symptoms that can range from mild to debilitating. Some of these symptoms are neurological: headaches, brain fog, cognitive impairment, loss of taste or smell, and even cerebrovascular complications such stroke. There are even hints that COVID-19 infection … Read more

Exercise Plus Cognitive Training Boosts MCI Improvement

SAN DIEGO — Among older patients with mild cognitive impairment (MCI), the combination of vitamin D and physical exercise plus cognitive training led to greater improvements than exercise alone. The findings were drawn from an unusual study design that split patients into five groups, one of which included both interventions. After the study was completed, … Read more

Regular Exercise Appears to Slow Cognitive Decline in MCI

Regular exercise, regardless of intensity level, appears to slow cognitive decline in sedentary older adults with mild cognitive impairment (MCI), new research from the largest study of its kind suggests. Topline results from the EXERT trial, which is the largest study of its kind, showed patients with MCI who participated regularly in either aerobic exercise … Read more

PTSD May Accelerate Cognitive Decline Over Time

Posttraumatic stress disorder (PTSD) is associated with accelerated cognitive decline over time, new research suggests. In an analysis of more than 12,000 middle-aged women who had experienced at least one trauma in their lives, those with PTSD symptoms showed an approximately two-fold faster decline in cognition during follow-up compared with those who did not have … Read more

Long-term Erratic Sleep May Predict Later-Life Cognitive Problems

CHARLOTTE, NC — Erratic sleep patterns over years or even decades, along with a patient’s age and history of depression, may be harbingers of cognitive impairment later in life, an analysis of decades of data from a large sleep study has found. “What we were a little surprised to find in this model was that … Read more

Simple Screening Tool Assesses Cognitive Impairment Post-COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The covered study in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway Patients with post-COVID syndrome have a long-term cognitive impairment that can last for more than 3 months and can … Read more

Residential Green Space Linked to Better Cognitive Function

Dr Marcia Pescador Jimenez Exposure to green space may boost cognitive function, new research suggests. Results of a large prospective study showing increasing exposure to residential green space was associated with significantly higher scores on cognitive function measures in middle-aged women compared with women who had less exposure. This association may be explained by a … Read more

Impaired Vision an Overlooked Dementia Risk Factor

Impaired vision in older adults is an underrecognized and modifiable dementia risk factor, new research suggests. Investigators analyzed estimated population attributable fractions (PAFs) associated with dementia in more than 16,000 older adults. A PAF represents the number of dementia cases that could be prevented if a given risk factor were eliminated. Results showed the PAF … Read more

Does Metformin Blunt Diabetes Link to Brain Aging?

researchers published the study covered in this summary on medRxiv.org as a preprint that has not yet been reviewed. Key Takeaways Type 2 diabetes appears to significantly accelerate normal brain aging. Metformin use does not appear to prevent neurocognitive decline. Why This Matters Although preliminary evidence links type 2 diabetes to neurologic and cognitive decline, … Read more

‘Staggeringly High’ Rates of Psychiatric Symptoms After COVID-19

DENVER — Neurocognitive and psychiatric symptoms of mental illness, including posttraumatic stress disorder (PTSD), are alarmingly high among patients who have previously had COVID-19 — even among those who were not hospitalized with the virus, new research shows. The findings are from an online survey of more than 800 respondents. “Regardless of how long ago … Read more